Re: Hereditary thrombophilias

From: Bernard Cristalli (bclaure@club-internet.fr)
Mon Jan 27 01:14:10 1997


Dr Vivienne Souter wrote: I would be very interested to hear from list members as to their approach including any experience with low molecular weight heparin and monitoring its effects in pregnancy and the use of Antithrombin III concentrate. > (What about protein C and S deficiences, Factor V Leiden and antiphospholipid antibodies?)
> Look forward to hearing your replies

For the women with a medical history of deep veinous thrombosis (or familial history of hereditary illness) I use low molecular weight heparin (LMWH). From the beginning of the pregnancy till the end, & some days after the delivery. I do the same thing for protein C & S deficiences & APL syndrom. LMWH do not pass the placenta due to their molecular size & are a lot more convenient with only one injection a day.

--
Bernard Cristalli MD CNGOF
Paris - France




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