Re: Hot flashes/phytoestrogens

From: KELLY SHANAHAN (mks@sierra.net)
Sun Jan 26 14:06:47 1997


>This sounds real "California" to me. Seriously:
>
>1. Are these woman rendered amenorrheic, a la Prempro, after a lead in
>adjustment time?
>
>2. I have been rather unimpressed with Prempro (or other continuous
>combined Rx) in women who are perimenopausal, or just into menopause, in
>terms of many of them not being amenorrheic after 4 to 6 months. Do you
>have a comment on that?

>Garry E. Siegel, M.D.
>Roswell, Ga.

Garry

Since I'm not a native Californian I won't take offense at your first comment :-)

Using continuous combined(CC) "natural" HRT is similar to using CC "big drug company" HRT. Most women will become amenorrheic after several months.

I usually give my perimenopausal/early-into-menopause patients the options of cyclic HRT (natural or otherwise). They're used to having a period so it may be less of a hassle to have predictable bleeding than unpredictable. I discuss both ways and let the patient choose. I use Premphase or a non-equine estrogen daily + Provera 5mg x 12 days or natural estrogens daily + miconized oral progesterone 200mg x 12 day (with the natural stuff I tend to dose it BID upon the recommendations of the pharmacists). After a year or so, after discussion, I'll try to switch the patient to a CCHRT regimen.

Hope this is helpful

--
Kelly Shanahan
S. Lake Tahoe, CA




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