Re: micronized oral progesterone

From: Bernard Cristalli (bclaure@mailhost.grolier.fr)
Mon Dec 30 14:15:12 1996


dahmd@gate.net wrote: >
> Dear colleagues-
>
> A number of patients are approaching me about using micronized oral
> progesterone (MP) instead of using medroxyprogesterone acetate (MPA, usually
> marketed as "Provera" in the U.S.). I have seen a few studies, including the
> PEPI trial, that support the use of MP over MPA. My take on the literature
> is that 100mg each day of the month as part of a continuous hormone
> replacement regimen, or 300mg/day for 10 days a month as part of a cyclic
> regimen, will result in atrophic endometria. (Others have suggested that there
> is not enough literature yet, and patients on MP should undergo an annual
> endometrial biospy to rule out hyperplasia/cancer). I also understand that
> taking this with food increases the bioavailability.
>
> Any pearls of wisdom from list members who use MP regularly? Many thanks in
> advance.
>
> Ashley
> D. Ashley Hill, M.D.
> dahmd@gate.net
> Orlando, FL

Hi,

Here you will have a few references…

--
Bernard Cristalli MD CNGOF
Paris - France




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