Re: mifepristone

From: Albert Ohayon (aohayon@ibm.net)
Thu Dec 5 02:41:25 1996


Robert J Woolley wrote: >
> For the American doctors on the list, I'm curious how many of you are
> thinking about offering mifepristone (RU-486) terminations to your
> patients when it becomes available next year? For our international
> colleagues, are any of you doing this already?

About Mifepristone, It is called Mifegyne in France, you can utilize it for abortion until 49 days of amenorrhea. You have to give 600 mg. Once and use prostaglandines analog from 36 to 48 hours after the RU. In the pratique, women have to take orally RU in your presence and come back to clinic 2 days after, have the prosta, injection or orally. Then often the abortion occurs, with bleeding. She can have a antalgique. She goes back home accompanied, 2 hours later. It works in more than 95%. You must verify the vacuity of uterus maximum 9 days after. You have to give a contraception. Excluded to this technique, hemostat troubles, cortosurrenal insufficiency, people with corticotherapy. Until now, we did not propose this to smokers. Because of cardio-vasc problems seen with another protaglandin analog on smokers. This year it seems not to be an motif of exclusion. I think that women who goes to this RU must be strong in her mind with the decision of abortion. The does all by herself so she feels completely responsible. Most of M.D. in France consider that it is a complication compared to the surgical way. Easier for us. The public hospitals goes on this technique, private breaks on it. RU is used to prepare cervix for surgical abortion, as we done before with « laminaires ». RU is used for Abortion in the second and third trimester. To prepare the cervix. It works very well. It is also used, in selected areas for the preparation of the cervix on « declenchement » of post term pregnancy, normal pregnancy. But no one will say that to you. It is experientially done. Well, hope I answered the question.

Cordialement. Merci !

--
etre humain ou ne pas etre, serait-ce la question ?...
Albert Ohayon, M.D.
Exercice liberal. Private practice.
Gynecologie/obstetrique
20 rue de la loge, 34000 Montpellier, France
Clinique Clementville




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