Re: sjogren's syndrome

From: douglas krell (douglas.krell@nsionline.com)
Wed Nov 27 12:40:48 1996


Michel Briex wrote: >

No result with progestins > during 20 days a month. Hysteroscopy shows endometrium hyperplasia.
> What would you do?

Bonjour Michel, Greetings from New Mexico, USA A few questions first. In this patient is hyperplasia a pathologic diagnosis or from visual inspection alone? Often patients who have been treated with progestins have a very thickened hyperemic appearing endometrium. Almost like a decidual reaction in pregnancy. An endometrial biopsy should be done. You may find an intense lymphocytic infiltration in which case hormonal therapy may not be the answer.

Is the patient interested in future reproductive function? It is rather unusual to have a premenopausal woman with Sjogren's Syndrome. Does she have a normal uterus with respect to size and configuration? An MRI may demonstrate adenomyosis or small miliary like fibromas. Perhaps an ultrasound would be another diagnostic test to consider.

What other manifestations of Sjogrens does she have?

Interesting case...let us know more details.

--
Douglas Krell MD FACOG
douglas.krell@nsionline.com




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