Re: Malaria Prophylaxis

From: Justin Ainsworth (skibum@pinsight.com)
Wed Nov 27 09:12:26 1996


The Primary Care Update For Ob/Gyn, V3, #6, Nov/Dec 1996 has an article on travel medicine and the author recommends chemoprophylaxis beginning at least 1-2 weeks prior to travel, to be continued for 4 weeks after leaving the endemic area. Current information from CDC at 404-639-1610 can be obtained regarding the appropriate agent for the area of proposed travel. Chloroquine is safe in pregnancy and lactation, however if chloroquine resistant malaria is present in the area, mefloquine (Lariam) is recommended. Mefloquine is not recommended in pregnancy, consequently travel to chloroquine resistant malarial areas has been listed as contraindicated in pregnancy. Women who must take mefloquine should not conceive for the duration of pregnancy and for two months follwoing its discontinuation. However if travel is unavoidable, CDC recommends that fefloquine be given, as malaria infection may be more severe in pregnancy.

Ron Ainsworth <ainsron@mem.po.com> Paradise, CA

At 12:17 AM 11/27/96 -0600, you wrote: >I have a patient going to East Nigeria for 4 weeks and she will be there
>from 7-11 weeks gestation. Any advice for malaria prophylaxis?
>
>Thanks.
>
>Geffrey H. Klein, MD
>listowner: OB-GYN-L
>gklein@bcm.tmc.edu
>gklein@icsi.net
>http://www.bcm.tmc.edu/obgyn/obgyn-ce/geff.html
>





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