Re: Nuchal Translucency

From: ATB28@aol.com
Wed Nov 20 17:17:30 1996


In a message dated 96-11-20 11:05:40 EST, mbriex@alienor.fr (Michel Briex) writes:

<< We use nuchal mesearement systematically at 12-13 weeks, if > 3mm we recommend amniocentesis for Down Sd diagnostic. If you find more than 1 or 2% you have to improve your measurement technic. >>

We also use these parameters.

It is likely that measurement of fetal nuchal translucency will be incorporated into the algorithms applied to risk assessment in screening for Down syndrome in the *first* trimester (e.g., hCG, Papp-A, and nuchal fold). Of course, this doesn't address the risk for NTDs (which MSAFP addresses in the second trimester) but then again, the ultrasound should pick this up.

(:-)

Other modalities likely to be added soon to our screening armamentarium:

(1) Maternal serum Quad test (AFP, hCG, uE3, and dimeric inhibin) for both DS and NTD.

(2) Urinary beta-core (second and later first trimester) for fetal DS.

Allan T. Bombard, MD Director, Reproductive Genetics Department of Obstetrics, Gynecology, and Women's Health Albert Einstein College of Medicine/Montefiore Medical Center Bronx, New York





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