Re: Ptyalism/sialorrhea

From: T-H Bui, Clinical Genetics, Karolinska Hospital (bui@gen.ks.se)
Fri Nov 15 04:00:32 1996


At 17.10 1996-11-14 -0600, "DR. Rafael Sánchez Usabiaga" wrote: > I have a similar case few months ago. I treat her with meclizine (bonine)
>dimenhydrinate (dramamine), and butilbromuro of hioscine (anticolinergic
effect) >with out good results.

Garry Siegel Roswell, Ga. also wrote: >>I have a patient who is 7 weeks with excessive salivation, and I can't find
>>much in any texts about possible treatments.

I don't have any expertise on this matter. However, a few years ago I also had a difficult case in a pregnant woman. I discussed it with a friend gastro-enterologist who suggested that this might due to gastroesophageal reflux, which is not uncommon in pregnant women or the result of unnoticed hiatal hernia. I didn't know then that stimulation of the esophagus by gastric acids leads to an 'esophagosalivary reflex'. The increased salivary flow neutralizes the acid content of the esophagus. My patient was therefore treated as for GE-reflux with Gaviscon, containing among other things aluminium hydroxid (10% Al2O3) and Natrium bicarbonate. This drug is commonly used here for heart burns during pregnancy. In addition the patient used an extra pillow at night. The results were excellent within 3-4 weeks. My suggestion is therefore that treatment is given as for GE-reflux.

***************************************************************** The-Hung Bui, M.D. =20 Associate Head Physician =20

--
Department of Clinical Genetics
Karolinska Hospital
S-171 76 Stockholm, Sweden

phone: +46 8 729 4989 or 729 2472 (secretary) fax: +46 8 32 77 34 E-mail: bui@gen.ks.se or The-Hung.Bui@molmed.ki.se ******************************************************************





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