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Re: Prader-Willi Syndrome From: Arthur W. Curtis, Jr. (artcurtis@juno.com) Thu Nov 14 14:40:07 1996 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: rbraun@indyunix.iupui.edu: "Re: Keillands: was Forceps Identification" Previous message: Richard Chudacoff, MD: "Keillands: was Forceps Identification" Maybe in reply to: George M. Grunert: "Prader-Willi Syndrome" Dr. Dhanda An excellent detailed description can be found in Birth Defects Compendium (Daniel Bergsma edit, March of Dimes) which includes the following references to diabetes: "Complications 1) Derived: Diabetes mellitus, adult type, without tendency to ketosis appears often during 2nd decade. Gastric perforations as a consepuence of overeating. Early development of arteriosclerosis has been described in a few cases. "Pathogenesis: A hypothalamic dysfunction has been assumed, yet post mortem examinations of the diencephalon have so far no revealed any pathologic alterations. A defect in the fat metabolism in association with an altered action of insulin has been conjectured as well." There is no mention of Maternal diabetes as being related to PW. It says males are infertile, but makes no mention of female fertility one way or the other. Some may have ovulatory but irregular cycles, normal estrogenization of vaginal mucosa and normal secondary sex characteristics. Presumably you have a mother who delived a PW baby, or do you possibly have a PW mother who is pregnant? If you do not have access to the compendium, eMail me and I will send you copies of the article. ____________________ Arthur Curtis -- ____________________ Worcester, MA ArtCurtis@Juno.com On Wed, 13 Nov 1996 23:00:26 -0600 (CST) "Paula R. Dhanda" <prani@pacific.net> writes: >I am trying to get information about Prader-Willi Syndrome. Does >anyone have references? Is there any known association with >Insulin-dependent diabetic mothers? > >Thank you >-- >****************************************************************** >Paula R. Dhanda, MD, FACOG, FACS >Lakeview Women's Specialty Group >Kelseyville, California >e-mail: prani@pacific.net > Next message: rbraun@indyunix.iupui.edu: "Re: Keillands: was Forceps Identification" Previous message: Richard Chudacoff, MD: "Keillands: was Forceps Identification" Maybe in reply to: George M. Grunert: "Prader-Willi Syndrome"

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