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Re: beta strep screeningFrom: Mats Bergstrom (matsb@cor.sos.sll.se)Thu Nov 7 18:59:41 1996
On Thu, 7 Nov 1996 Terrence.Jones@ncal.kaiperm.org wrote: (Thanks for a good resume - and for paragraphing.)
> with vaginal (not cervical - which would be lower) c/s = 59%, for I don't know which studies ACOG bases their recommendations on but I doubt there are that many, if any, longitudinal investigations comparing outcome with culturing from different locations or with different methods with differing sensitivity. It is possible that clever culturing might raise the rate of positive's considerably, calling for treatment of the greater part of the pregnant population, without improving the overall outcome one bit, since there is very likely a strong relationship between the infective dosage and risk of clinical infection. Strictly speaking, the benefit of intervention has only been shown for those methods/sites of culturing that were used in the relevant studies.
> criteria for risk factor chemoprophylaxis. When they reduced the If you reduce it to 10 minutes you would pick up close to 21/21 cases. The infective dosage is depending on the ROM interval to some degree, but this kind of statistics doesn't really reveal the point of discrimination based upon cause-effect, but mostly shows that the mean interval of labor after ROM is shorter than 18 hours.
-- Mats Bergstrom, MD Ob Gyn South Hospital Stockholm
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