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Re: HRT and choleithiasis From: Terrence.Jones@ncal.kaiperm.org Tue Oct 29 00:13:56 1996 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: T-H Bui, Clinical Genetics, Karolinska Hospital: "Re: twin-twin transfusion syndrome" Previous message: George Saade: "Re: twin-twin transfusion syndrome" Maybe in reply to: Masato Sasaki: "HRT and choleithiasis" Next in thread: R. Daniel Braun: "Re: HRT and choleithiasis" Joe, thought I'd add my 2 gms of lard, or crisco, of other fast-food derivative... Had a pt. with recurrent biliary duct stone post-chole, removed endoscopically, along with ampullary dilation. She wanted to continue PERT (HRT) and her GI Doc said it would be OK considering she had ampullary dilation. The Pt had questions regarding lithogenic tendencies of oral Vs transdermal. Found a article by Van Erpecum from 1991, (Gastroent. 4/91, vol 100:482-88). The numbers were small (17 pts) and demonstrated the usual rise in E1 (estrone), associated with oral estradiol compared to trans- dermal (secondary to first pass hepatic metabolic fx). However, there was a subgroup in which the rise was much higher (E1 more than 0.5 pmol/ml, n=8). These pts had an increased biliary saturation index on oral estradiol that was not evident on transdermal. Anyone have any experience with estrogen and pts with CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalo- pathy)? (Weller, Neurology 3/96, 46:844). Terry. Next message: T-H Bui, Clinical Genetics, Karolinska Hospital: "Re: twin-twin transfusion syndrome" Previous message: George Saade: "Re: twin-twin transfusion syndrome" Maybe in reply to: Masato Sasaki: "HRT and choleithiasis" Next in thread: R. Daniel Braun: "Re: HRT and choleithiasis"

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