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Re: Cytotec inductionFrom: DrBryan@aol.comMon Oct 21 20:11:41 1996
I just started looking this up. See Mundle, et al, "Vaginal Misoprostol for Induction of Labor," Ob Gyn 1996; 88:521-5. Patients who met reasonable criteria had a 50 microgam tablet (half of the standard 100 mcg. dose) placed in the fornix q 4 hrs. until labor occurred. They were compared to a Prostin group and there were no significant differences (e.g. C/S rate, hyperstim rate, low apgars, etc.) Other protocols referred to are 25 mcg. q 2hrs., 50 mcg. q 3 hrs., or 100 mcg. given once, but these were not addressed in this paper. What I would like to see is a study where we place a single misoprostol in the fornix in the office at 4:00 p.m., monitor, then send home, and begin the induction the next morning. Anyone brave enough? Bryan Jick, M.D. Pasadema, CA. It was 72 degrees and sunny today!
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