Cord blood for stem cell transplant

From: Kenneth J. Moise (kmoise@bcm.tmc.edu)
Sun Oct 6 18:47:49 1996


I was recently involved in a preliminary meeting with our regional NOT-FOR-PROFIT blood center in Houston to discuss the possibility of collecting cord blood at delivery for stem cell transplants. UNLIKE the commericial ventures that have been recently advertised, we would have the patients sign a consent that would donate the cells to a centralized bank much like standard blood donation. These cells would be HLA typed and then frozen, The cell would be available to the general public for transplant through a computerized database.

The question arose as to whether obstetricians would be willing to routinely harvest this blood at delivery. The apparatus might be as simple as a needle connected to a collection bag with anticoagulant. The umbilical vein would be cannulated and the blood allowed to drain by gravity. Once the cord was drained, the bag would be clamped and sent to a central refrigerator area for subsequent pickup. Blood bank personell would secure consent on the first postpartum day. (Alternatively, the obstetrician could obtain consent during the prenatal course.)

What are the list subscribers' opinions on this topic? Would you be willing to participate as the blood collector?

Ken Moise Baylor College of Medicine





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