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Re: Tamoxifen and endometrial changesFrom: "Francisco L. Romero Aceña" (fromero@adam.es)Sun Oct 6 18:23:10 1996
ATamoxifen, I suspect that vaginal >>ultrasound may well become the screening method of choice in patients taking >>this drug. However, I would not have advised annual TVUS in this >>particular patient. >> >I'm aware of one paper which suggested that tamoxifen produces artefacts >in U/S appearance of endometrium. The authors postulated that there was >some density change in sub-endometrial myometrium which made it look >like thickened endometrium. In our Department, we use to do Ultrasound follow up yearly. When endometrium images are thick or heterogeneous, we practice a sonohysterogramm and can see if it is a subendometrial artefact or if it is a endometrial lession such a pollyp. It is very quick usefull and cheap. If sonohysterogramm make us suspect afected endometrium we indicate the hysteroscopy.
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