Ablation and 14 week fibroid uterus-reference

From: Malcolm Griffiths (Malcolm@mgriff22.demon.co.uk)
Fri Oct 4 12:47:53 1996


In message <960929122623_296326182@emout14.mail.aol.com>, ENDODOK@aol.com writes >Re: Ablation for a 14 week fibroid, I personally would not recommend it as
>the chance of success is low. I further have never seen or read a report of
>a large fiboid uterus "shrinking" significantly after a submucous resection,
>followed by endometrial resection/ablation.

? Reference is to a paper which showed that pre-treatment with LH-RH analogues followed by endometrial resection shrunk fibroids and they did not re-grow. Postulating an endometrial "fibroid growth factor". ICI manufacturers of the Zoladex used in the study/case series have no record of any later substantive work ( I asked them last month !!! ). Reference is: Slade et al Endometrial resection after GnRH analogue therapy - a possible new treatment for fibromyomata J.Obstet.Gynaecol. ( the red one ) 1993;13(6):286

--
Malcolm Griffiths               MD,MRCOG,MFFP,Cert.Mgmnt
Obstetrician & Gynaecologist    Luton & Dunstable Hosp.,UK.
Tel:    01582-497459 (office)
        01525-222849 (home)
Fax:    01582-497424
email:  Malcolm@mgriff22.demon.co.uk

"It is dangerous to be right on a subject on which the established authorities are wrong." (Voltaire)





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