Re: Following an Ectopic and...

From: David A. Nagey, M.D., Ph.D., FACOG (dnagey@welchlink.welch.jhu.edu)
Wed Jul 31 23:04:32 1996


Geffrey H Klein, MD wrote: >
> Hi all....
>
> Need some help with a case.
> As you may know, I have finished residency and I am now in private
> practice. What a change..
>
> Anyway..
>
> Please advise:
>
> I have a patient who presented to the ER complaining of classical symptoms
> of ruptured ectopic.
>
> She is a 25 y/o G4P1A3 (all spontaneous Abs) who was hemodynamically
> unstable and underwent emergent exploratory laparotomy. She desired to
> preserve fertility if possible. At that time she had a 750 cc
> hemoperitoneum and a ruptured right ampullary ectopic. The contralateral
> side was grossly normal as was the distal portion of the affected side. I
> resected the ruptured portion (salpingostomy would have been impossible)
> with the idea that if she got a contralateral ectopic, the right side could
> be re-anastamosed. (In retrospect, I am not sure if I should have done
> that). In any event.. The pre-op quant was 6000. Postop the patient did
> well and went home. The path returned as trophoblastic hyperplasia in the
> specimen with a recommendation to follow betas as if it were a molar
> pregnancy. She was started on contraception, but at the office admitted
> that she had had unprotected intercourse.
>
> Betas as follows: 7/15 167 7/17 103 7/24 111
>
> Now she complains of some vague abdominal discomfort and spotting.
>
> I took the slides for review by a gyn onc pathologist who concurs that the
> specimen contains trophoblastic hyperplasia.
>
> Any suggestions on how to proceed? Methotrexate? Scope? Follow betas
> some more?
>
> help!!!
>
> Geffrey H. Klein, MD
> listowner: OB-GYN-L
> gklein@bcm.tmc.edu
> gklein@icsi.net
> http://www.bcm.tmc.edu/obgyn/obgyn-ce/geff.html

wait a few days and repeat the hCG's - in these days of managed care, I wouldn't trust the lab as much as I did 15 years ago....

David





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