Re: Calcium channel blockers?

From: Dr Eberhard W Lisse (el@lisse.na)
Wed Jul 31 12:17:50 1996


Ricardo,

At 12:19 PM 31/7/96, SAVARIS@vortex.ufrgs.br wrote: >DEar Joe
>
>Calcium block channels and tocolis...
>When I was resident I took all the articles that I found for all my journal
>club to try to put this drug in our protocol...non of the articles convinced
>the Head of the department and the current saying here is against Calcium block
>channels for tocolisis.

We don't use Magnesium here and would use iv Hexoprenaline (Ipradol).

What has made my midwives true believers is that Nifedipine does stop the contractions better then the 150 mcg (micrograms :-)-O) of Hexoprenaline in 1 L D5W titrate to pulse rate > 120 or contractions stop which my other colleagues still give.

I write Nifedipine 10 mg 6 hourly po/sl and the usual Hexoprenaline regime on standby at the midwive's discretion if the contractions don't stop. This might convince your Head of Department to try, because if there is no response one can immediately whack them with the beta-stimulant.

>We use it for Pre-eclampsia as first drug for hypertensive crisis sublingual
>(under the tongue) and for short time. I never saw any case of hypotension.
Neither did I. On a recent CME the cardiologist even said that Ca Blockers don't lower pressure much in normotensive patients.

greetings, el

--
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