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Re: Calcium channel blockers?From: Francisco L. Romero (fromero@adam.es)Tue Jul 30 16:07:31 1996
>Well, we have pretty much covered indomethacin. I would like to know what the >Group thinks about the calcium channel blocked and tocolysis. Specifically, >any concerns about hypotension, decreased uterine blood flow, IUGR, etc? > In our protocol we use nifedipine: loading dose: 20 mg sublingual and wait 20 minutes for any tocolytic effects if no effects give 10 mg sublingual and wait 20 minutes more if no effects give 10 mg sublingual again if no effects choose a different tocolytic. if nifedipine works keep a dose of 20mg oral /6 hours for 24 hours and , then, keep 10 or 20 mg /8 hours. As I told in other mails our first choice tocolytic is Ritodrine, a beta-mimetic. We use nifedipine when beta mimetics are contraindicated: cardiopathy or diabetic women. We consider contraindicated in alergic, nefropathy. In my personal experience, i have obtained good results in that women with uterine dynamics but no cervix modifications. I prefer use nifedipine better than ritodrine that has more side effects. I have no detected hypotension in women previously with normal pressure. The most common side effect i have seen is skin flushing and headache. The two both have always been spontaneously autolimited. excuse my English spelling. I'm learning not only OBGYN reading the list, I learn, slowly, a bit of English spelling. Thanks for your patience. ---------------------------------------------------------------------------- Francisco L. Romero. MD, S.E.G.O. member. ---------------------------------------------------------------------------- ---------------------------------------------------------------------------- ---------------------------------------------------------------------------- OBGYN Department. Hospital General de Catalunya. S.Cugat del V. (BARCELONA) OBGYN.net Spanish International Representative. e-mail: fromero@adam.es http://webs.adam.es/fromero/myweb.htm ----------------------------------------------------------------------------
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