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Re: Premature menopauseFrom: DoctorJoe@aol.comMon Jul 22 08:57:35 1996
<< I find myself with four young women (under 40) with premature menopause manifest by amenorrhea and elevated FSH, all desirous of childbearing. Do any of you have references, protocols, or anecdotes relating to management or potential for childbearing. One of these women actually got pregnant after being treated with high dose estrogen by one of my colleagues (I sectioned her for a breech and found streak ovaries. Chromosomes were normal). My understanding is that estrogen by suppressing the elevated FSH may allow any residual follicles to ovulate, and that premature menopause may be a relative not absolute state.>> I've seen a NUMBER of women who are: 1) usually prematurely grey (I've seen that defined as over 1/2 of your hair turns grey before the age of 40); 2) tend to have "slightly" irregular periods (slight enough that if you don't specifically ask them about times and dates, they just 'assume' that it's normal for their age; 3) develop almost "status PMS" -- they seem to have constant symptoms of PMS, occasionally worse premenstrually, but not always; 4) have similar histories in a number of female family members (including older family members with marked osteoporosis). So far, none of these women have tried to get pregnant. I would assume (since I'm a MFM person and not a REI person) that they can be managed just like ANY perimenopausal patient, depending upon what you want to get out of it. ************************************************* doctorjoe@aol.com "All things are connected. Joseph Pastorek, MD Some things are just more Department of OB-GYN connected than others." LSU Medical Center - Dirk Gently New Orleans, LA ("The Big Easy") U.S.A. *************************************************
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