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Re: acyclovir in pregnancyFrom: DoctorJoe@aol.comThu Jul 18 08:54:38 1996
<<what is your opinion (and practice) re: use of acyclovir in non-immunocomprimised pregnant women for 1) primary HSV outbreak 2) recurrent HSV outbreak 3) prophylaxis to reduce chance of outbreak near term?>> Officially, I think acyclovir is only used during pregnancy for evidence of severe maternal disease (e.g., hepatitis, encephalitis). However... 1) I think in a primary infection, especially with systemic symptoms, you can get some mileage out of acyclovir in shortening the outbreak and ameliorating symptoms. After all, besides not wanting dissemination, you would like not to have systemic symptoms incite uterine activity, etc. 2) I don't think people routinely use acyclovir for simple recurrences during pregnancy. 3) Acyclovir as prophylaxis near term (meaning, acyclovir as prophylaxis against C-section) is, if I'm not mistaken, being looked at in a study somewhere right now. Maybe Zane Brown up in Seattle??? ************************************************* doctorjoe@aol.com "All things are connected. Joseph Pastorek, MD Some things are just more Department of OB-GYN connected than others." LSU Medical Center - Dirk Gently New Orleans, LA ("The Big Easy") U.S.A. *************************************************
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