Re: Twins discrepancy

From: T Dubose (tjdubose@chrp.uams.edu)
Thu Jun 27 09:06:23 1996


"What would you do?" Being a sonographer and not a physician, I would study them and measure them. No help here, however, I think there are things we can not fix or avoid.

Now a further question concerning this case and particularly the one I described here yesterday. In our case of discrepant growth, the twins were monochorionic, diamniotic, and genetically identical, physically normal, but different sizes. Because there was a consistent 1 week difference in size from the 1st exam at 6 weeks until the 24th, when the discrepancy began increasing, the following questions: Is it possible for the blastocyst to split into unequal cell masses and result in discrepant growth? This might explain the difference in size in the first half of the pregnancy. Or, how soon could a mild degree of twin-to-twin transfusion start effecting the pregnancy without causing sever problems, just a 25% difference in size? It seems this latter scenario is improbable because a tttt that affected size that early should be fairly severe and end in disaster for the pregnancy. Just curious if anyone out there may have an academic interest in this problem and maybe some answers.

Peace, Terry J. DuBose, M.S., RDMS; Program Director, Diagnostic Medical Sonography University of Arkansas for Medical Sciences, College of Health Related Professions tjdubose@chrp.uams.edu http://www.io.com/~dubose/ Now is the time for all good folks to come to the aid of the Earth.

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From: SAVARIS@vortex.ufrgs.br
To: Multiple recipients of list
Subject: Twins discrepancy
Date: Wednesday, June 26, 1996 9:19PM

For the ones who wanted the original case from the twins.

and few more answers.

I dont know why the discrepancy of their weight, one reasable answer that cross my mind is that htey were diamniotic, dichorionic.

Why the babies died? Baby #1 (800g) died just after the delivery, I dont have the necropsy, but I will try to find, but for some strange reasons necropsy is not always done in the babies. I have heard that the parents have to pay for the pathology (1200 USD) BAby #2 (1200g) died from hyaline membrane in the day after.

Desaceleration type 2 is late desaceleration.

The original case. A primigest, 24 yold, female, started with premature labour at 24 weeks. Ritodrine was tried with no success. The cervix reached 7 cm. The day before the Biophysical profile was 5/8 for #2 and 4/8 for #1. At US the #1 was at vertix apresentation and #2 transverse.

During monitoring, both babies presented late desaceleration, and number #1 persistent bradicardia. My collegue decided to performe emergency C/S.

What would you do?

Ricardo Savaris Porto Alegre, Brazil





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