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Re: Amniocentesis with anticoagulationFrom: T-H Bui, Clinical Genetics, Karolinska Hospital (bui@gen.ks.se)Thu Jun 27 08:32:44 1996
At 14.59 1996-06-26 -0500, Gary Kaufman wrote: > I have an anticoagulated patient (sq heparin) because of DVT during >the current pregnancy. > > Is anyone aware of information regarding the risk of genetic >amniocentesis in an appropriately anticoagulated patient? > Dr Kaufman, I am not aware of any refs on this subject. However, we have performed a few amniocentesis on patients receiving prophylactic low dose heparin (subcutaneous) because of previous DVT. They just avoided the morning injection and came to the clinics the same day for the procedure. APTT should be normal in all cases (more than 12 hrs since the last injection). We haven't had any complications, outcome were all normal (babies) although one mother had bone compression in the spine secondary to the heparin treatment. Amniocentesis should of course not be carried out if the patient is receiving full dose heparin for newly diagnosed DVT. I would not hesitate to perform an amniocentesis under the premisses discussed here. Hope this help. The-Hung Bui, MD Associate Head Director Fetal Diagnosis Program Dept. of Clinical Genetics, Karolinska Hospital, S-171 76 Stockholm, Sweden Consultant Obstetrician-Gynecologist (Fetal Medicine) Dept. of OB&GYN, Huddinge University Hospital, Karolinska Institute, S-141 86 Huddinge, Sweden phone: +46 8 729 4989 (office) or 729 2472 (secretary) fax: +46 8 32 77 34; e-mail: bui@gen.ks.se
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