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CA 125 and Serous ovarian tumor of low malignant potentialFrom: Peter V. Weston, M.D. (weston@ICSI.Net)Mon Jun 24 21:03:47 1996
I would appreciate help from the list members in managing a patient. 31 year old nulligravida who is currently not sexually active. She presented with vageu lower abdominal symptoms. Examination showed a large pelvis mass. U/S showed a 15.2 X 9.7 X 8.9 cm cystic mass with internal pappilations. No free fluid. At surgery, apart from the cystic mass which was removed intact everything looked normal. Specifically there was no free fluid, no endometriosis and no leiomyomata. The left ovary was normal but a wedge resection was performed. Cell washings were negative, the wedge resection showed normal ovarian tissue. The final pathology report showed "A serous tumor of low malignant potential. Neoplasm entirely confined within the ovary with no demonstrable surface involvement." Intraaoperative CA 125 was 50.2 U/ml. THREE WEEKS LATER THE CA 125 WAS 52.2 U/ml. QUESTIONS 1. What is the half life of CA 125? 2. How rapidly would you espect the rate of CA 125 to drop? 3. How often should one repeat the test? Or should we ignore this result? 4. What other tumor markers would y'all look for? 5. How actively should one follow a slightly elevated CA 125 in such a patient? Thank you! Peter
-- Peter V. Weston, M.D. weston@icsi.net Soon to relocate to Clear Lake to become a live-aboard! My e-mail address will not change.
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