Re: twins/maternal age counseling

From: ATB28@aol.com
Thu May 30 20:59:58 1996


In a message dated 96-05-30 15:31:43 EDT, Malcolm@mgriff22.demon.co.uk (Malcolm Griffiths) writes:

>Could you explain the basis for this please. Are you simply saying that
>if she's carrying twice as many babies she's twice as likely as any
>other 32 yo to have an aneuploid fetus ?
>--

The data comes out of Parkland, and has been presented at the SPO (?93 ?94...I could look up but it will be in the abstracts edition of the gray journal).

I had hoped to be clearer - apologies for failure to do so: the risk of a 32 year old with twins is roughly equivalent to that of a 35 year old with a singleton fetus. Thus, if your age threshold for offering genetic counseling and prenatal diagnosis is 35 years at term for singletons, you should use age 32 years if your patient has twins (I know of no concensus data for triplets and beyond).

We concur with the other respondents regarding the use of targeted ultrasound imaging, for all of the reasons cited.

Allan





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