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Ceredase and pregnancyFrom: Gary Kleinman (fuf@gulf.net)Tue May 14 13:11:52 1996
Please advise 26 year old g2p0 with type I (non-neuronopathic) Gaucher's disease. Pt on Ceredase (enzyme replacement) for 4 years with good results. Pt had throbocytopenia, anemia and bone pain when not on medicine. She is now 7.5 weeks post LMP and has not taken any Ceredase during pregnancy. Literature search came up negative for this therapy during pregnancy. We have a call into Genzyme Corp. to ask if they have data. I suspect that they might be very cautious with this agent durng pregnancy because of liability risks. Hematologist wants to start it in a little more than a month (after the 1st trimester). Would anyone prescribe this agent during pregnancy? Thank you for your advice. gary
-- Gary Kleinman, MD Perinatologist/Geneticist University of Fl/Pensacola 5045 Carpenter Creek Drive Pensacola, FL 32503 904 484-9400
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