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(Fwd) Re: Amnioscentesis [sic.]From: prenatal@hospital.oshawa.on.caTue May 7 16:20:52 1996
Regarding: Risks and benefits of amniocentesis (and serum screens) My only addition to Allen Gardner's comments is that the "MSS" he relies on is the "triple test" (AFP, uE3 and hCG) which has a detection rate of at least 75% in 34 year old patients. The original message talked about having the "AFP test" in a 34 year old patient and the detection rate with this single test is much lower than the triple test, perhaps 40 or 50% in 34 year old patients. If serum screening is to be used in the consideration of the risk/benefit of amniocentesis, then I would suggest having the three-marker serun test rather than just MSAFP. A. MacRae, Ph.D., FCACB Whitby, Ontario, Canada Original meeage from: Allen Gardner <allen.gardner@utoronto.ca> Subject: Re: Amnioscentesis [sic.] 2 comments re your dilemma: 1. We recently completed an audit of about 5-6 years of amnio experience and our miscarriage rate was 0.5%. This included all mishaps following amnio, even if the time span suggested no cause-effect relationship. I quote 1/200 as the risk and everyone in this part of the world (Ontario) does too. 2. I rely heavily on MSS, even to the extent of guiding the >35s out of amnio. Decision making is not easy and I sypathise with your dilemma. I'm glad we had our family before amnio exploded on the scene. Best wishes. Allen. On Thu, 25 Apr 1996 15:41:07 -0400 Bert Gold wrote:
> From: Bert Gold <bgold@itsa.ucsf.EDU> Allen Gardner MD Genetics Oshawa General Hospital Oshawa, Ontario, Canada
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