Re: Enhancing fetal lung maturi

From: R L Meisel (mfm@southwind.net)
Mon Apr 29 10:10:42 1996


>Joshua is of course right. I did mean IM, not PO. However the usual >doing interval around here is 12 hours, not 24; and it is usually 12 mg.

Does anyone have a rational explanation for the route and timing of the steriod reccommendations by the NIH?

Consider the following...

1. Oral or IV achieve higher serum levels than IM injection.

2. Long biological half-life ( 36-72 hours).

(Goodman & Gilman 8th ed)

Just interested in other list members thoughts.

Ric ******************************************************** Richard L Meisel, M.D., FACOG Division of Maternal-Fetal Medicine UKSM-W Dept of Ob/Gyn (316) 688-7990

3243 E Murdock St., Suite 201 FAX 688-7656 Wichita, Kansas 67208 mfm@southwind.net ********************************************************





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