Antiphospholipid Syndrome?

From: Gary Kaufman (gkaufman@bu.edu)
Thu Dec 28 21:12:45 1995


I just met a patient with a 16 week IUP and a moderate sized right sided DVT on doppler. Interestingly, she's had two prior losses, including a second trimester fetal demise. On admission (and before heparin was started) her platlet count was 60 and PTT normal. In her old chart is an anticardiolipin done in 7/94 at Igg 32.5 gpl (< 23 normal).

Given the positive ACL, fetal losses, thrombocytopenia and thrombosis it seems like antiphospholipid sydrome is a safe bet.

Recommendations regarding long term therapy -

SQ heparin at 12,000 units bid? Role of low molecular weight heparin, prednisone, asa?

Thanks,

- Gary Kaufman MD Boston City Hospital, Boston MA gkaufman@bu.edu GKAUFMAN@BU.EDU <Gary Kaufman>





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