Re: Magann, Am J Ob/Gyn 1994;171:1148

From: Dr Eberhard W Lisse (el@lisse.NA)
Thu Dec 28 12:25:32 1995


At 1:35 PM 27/12/95, Gary Kleinman wrote: [...] >The fetus measured 1250 grams; the AFI was 11 and the umbilical doppler ratio 3.4/1. The fetal tracing was reassuring. She was started on magnesium and given betamethasone, 12 grams IM.
Do I read this as 12g bethamethasone?

>Steroids were repeated at a dose of dexamethasone 10 mg IV bid continuously.
I don't underdstand this one either, 10 mg ivi bd every day?

>Magann et all have published (in a group of 25 patients) that bid high doses of dexamethasone till delivery extended the latent period (admission until delivery) of HELLP syndrome from 15 to 41 hours. Should I keep the
Latent Period? Are there predictive phases to HELLP? I didn't know that? Can you please let me have a copy of the article (snail mail or fax?)

>high dose of steroids? Magann reported worsening HELLP post partum after the steroids were stopped.

>Has this work been confirmed? Any suggestions?

I have no idea, other then dexamethasone will certainly not do harm.

I'd like to hear more, this is extremely interesting because it would give me more time with the referral to the National Hospital...

el

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