Re: Short cervix progesterone and twins

From: R. Daniel Braun (rd.braun@gmail.com)
Tue Sep 30 11:58:05 2008


I would quit sending anyone to that MFM. Some people are real full of themselves. Dan

On Tue, Sep 30, 2008 at 10:53 AM, Henry Gregor <henrygregor@yahoo.com>wrote:

> Re efficacy in twin gestations...is anyone aware of work that looked at
> twin pregnancies in different categories of twins in a patient with a prior
> hx PTL in a singleton pregnancy, vs twins in a patient without prior hx of
> PTL? I have a bit of an emotional interest here, I suppose, as I had a
> patient in the first category who elected on an informed consent basis to go
> with progesterone in her twin gestation, given her past hx singleton PTL,
> ... only to get flamed by a local MFM who told her the mgt we agreed on was
> without merit. (Pt did go to 36 weeks, though of course its only an
> anedcotal case observation.)
>
> Hank
>
> --- On *Tue, 9/30/08, R. Daniel Braun <rd.braun@gmail.com>* wrote:
>
> From: R. Daniel Braun <rd.braun@gmail.com>
> Subject: Re: Short cervix progesterone and twins
> To: "Multiple recipients of list OB-GYN-L" <ob-gyn-l@mail.obgyn.net>
> Date: Tuesday, September 30, 2008, 8:11 AM
>
> The first study by Johnson in the 70's, included twins and trips. It did
> indeed show efficacy.
>
> Dan
>
> On Mon, Sep 29, 2008 at 10:43 PM, Garry E. Siegel, M.D. <
> garrys@mindspring.com> wrote:
>
>> Nope.
>>
>> Needs steroids (done, I'm sure).
>>
>> My recollection is that 17 alpha hydroxyprogesterone caproate is advised
>> for prematurity prevention in singletons beginning at 16 weeks with no
>> known benefit for twins.
>>
>> Garry
>>
>> At Mon, 29 Sep 2008, Andrew Folley wrote:
>> >
>> >Morning rounds yesterday. Residents have 28 weeks Di/Di twins with short
>> cervix 12 mm. They have her on progesterone suppository 200mg q hs.
>> >I say fine but no evidence to support benefit of progesterone suppos in
>> twins. Benefit for delaying preterm birht only in singletons (de Fonseca
>> NEJM august 2007) MFM disagress with me. Anyone know of any new articles
>> study that show benefit for progesterone and twins? andy
>> >
>> >.

>>
>> --
>> Garry E. Siegel, M.D.
>> Private Practice
>> Roswell, GA
>>
>
> --
> R. Daniel Braun, MD FACOG(L) ABMP CMTh
> Professor Emeritus
> Dept. of Obstetrics and Gynecology
> Indiana U. School of Medicine
>
> R. Daniel Braun
>
> "Science without Religion is LAME; Religion without Science is BLIND"
> Einstein 1941
>

--
R. Daniel Braun, MD  FACOG(L)  ABMP  CMTh
Professor Emeritus
Dept. of Obstetrics and Gynecology
Indiana U. School of Medicine

R. Daniel Braun

"Science without Religion is LAME; Religion without Science is BLIND" Einstein 1941





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