Re: 17 oh progesterone
From: Andrew Folley (agfolley@hotmail.com)
Sat Jun 9 11:00:41 2007
Steve
I know there is some controversy around weekly use of 17 OH Progesterone but
I believe that there is evidence in literature based on Meis studies in late
90s and that doing so would decrease recurrent preterm birth rate by half.
ACOG has a committee opinion on thsi from Nov 2003. Also NIH of Child
Health and Human Development (NICHD) have data showing benefits of using IM
17 OH progesterone for asymptomatic women with history or prrevious
pretermbirths. Others help me out here if possible.
andy
>From: "Raymond Stephen" <stephen.raymond@dhhs.tas.gov.au>
>Reply-To: ob-gyn-l@obgyn.net
>To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net>
>Subject: RE: 17 oh progesterone
>Date: Fri, 8 Jun 2007 19:47:37 -0500
>
>There is no evidence that progestagen therapy benefits any pregnancy.
>The most one might do for this lady is to put in a cerclage at 16-18
>weeks, and even that would be debatable.
>
>I would like to know as well whether she has Bacterial Vaginosis.
>
>Steve
>
>-----Original Message-----
>From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Andrew
>Folley
>Sent: Saturday, 9 June 2007 12:48 AM
>To: Multiple recipients of list OB-GYN-L
>Subject: Re: 17 oh progesterone
>
>I have 3 ladies I am considering starting on 17 OH P at 20 weeks. #1
>had an
>incompetent cervix in first pregnacy with rescue cerclage at 24 weeks
>and
>preterm deliviery at 29 weeks. #2 developed severe preeclampsia and and
>was
>induced and delivered early at 28 weeks. Finally #3 more delivered
>second
>baby at 34 weeks following PROM. Do you think it is inappropriate to
>manage
>them with weekly 17 OH-P at 18 weeks etc??
>
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