Re: Cytotec

From: Dr Eberhard Lisse (el@lisse.NA)
Mon Apr 9 16:24:44 2007


Who's responsible if you prescribe 25 mcg and they administer 35?

Nevermind that I think this "generic = crap" is total nonsense, since the FDA approved the generic stuff and you are not buying from India.

el

on 4/9/07 8:05 PM art fougner, md said the following: > Why not the director of the hospital's pharmacy to supply you with the
> data supporting their use of the generic, eg bioavailability?
>
> Art
>
> At Mon, 9 Apr 2007, Richard Chudacoff wrote:
>> I moved to a new hospital in Las Vegas. They won't let us use Cytotec
>> orally, because it can't be washed out. However, we all know that after 20
>> minutes you can't wash it out vaginally, either. Not a big deal as the
>> nurses are allowed to put it in vaginally, but here is the problem. They use
>> GENERIC Cytotec (I guess at $0.50 a pill it was too much). Since we know
>> that generics can have a little as 80% and as much as 120% of the active
>> ingredient as the brand name, and since we now that the active ingredient is
>> not evenly distributed throughout the pill, cutting the pill to get a 25
>> microgram dose seems totally inconsistent with following an established
>> protocol as described in the literature. Here we have a chance of as little
>> as 15 or as high as 35 mcg but at a 50 mcg dose we can be as low as 30 or as
>> high as 70mcg. Am I figuring this out wrong or could we be headed for
>> disaster by using generic pills?
>>
>> --
>> Richard Chudacoff, MD, FACOG





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