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Prolonged PP fever + FRI: PlutoFrom: Terrence.Jones@kp.orgFri Aug 25 19:44:06 2006
This is a multipart message in MIME format. --=_alternative 0003FEDC882571D6_ Content-Type: text/plain; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable I see Betsy, Thanks. Sort of expected Your MFM's were following that line of reasoning. Pre-E is our Residents' abbreviation for preeclampsia. (Think of all the syllables saved at the end of a single day!) Did She have any bp elevation? Any chance the placenta might have been sent? Guess I already know the answer... Was enlightening to see, in the Mercer series, that Pre-E was 3-4X more prevalent than chorio, in SPT. Demonstrates that inflammation is not always infectious. Guess You get enough local exposure to the anti-thromboembolic mechanisms involved (Paidas, Semin Perinatol 2005, 29:150-63). But also think it's interesting that attn is turning to immune modulating effects of Heparin (Salmon, Nat Med 11/2004, 10:1222-26). /tj FRI: Sad news about Pluto. Heard Xena started the whole mess - thought they thru Her off the air? Just shows Ya' - if you're a little smaller, and keep to the periphery, those on the inside will kick You out! Just wait'll Neptune starts wandering toward the Kuiper belt, then next on the block is Uranus. >:) NOTICE TO RECIPIENT: If you are not the intended recipient of this e-mail, you are prohibited from sharing, copying, or otherwise using or disclosing its contents. If you have received this e-mail in error, please notify the sender immediately by reply e-mail and permanently delete this e-mail and any attachments without reading, forwarding or saving them. Thank you. Betsy Hyde <elishyde@mindspring.com> Sent by: ob-gyn-l@obgyn.net 08/25/2006 15:01 Please respond to ob-gyn-l To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net> cc: Subject: Re: prolonged PP fever On Aug 25, 2006, at 5:39 PM, Terrence.Jones@kp.org wrote: These regional differences are always interesting. After the description per Mercer & Sibai (JMFM 1996, 5:355-8), and the comparitive trial per Cunningham (AJOG 1999, 181:143-8), Our MFM's actually discourage heparin, in absence of thrombus on imaging. The heparin was discouraged/delayed because we were told there was no good evidence that it helps if the dx is spt, and that time to defervesence does not vary based on use/nonuse of heparin if there was spt. This, apparently, was from the Cunningham Study. Drs. Magann & Martin (Hypertens Pregnancy 2004, 23:121-7) demonstrated, as You have in this case, that the premorbid state does not always include variables associated with infection. Chorio was present in only 13% of SPT; in their 9 year series of 55 postpartum Pts. Instead, the condition may be more of an aberrant endothelial response (Pre-E present in 45%). Did Your Patient have any stigmata (of Pre-E)? I don't know what the stimata of Pre-E (or even what Pre-E is....ok, I'll 'fess up) are, and either don't know/can't remember her labor course. Sorry. \Betsy Hyde CNM Branford, CT --=_alternative 0003FEDC882571D6_ Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable <br><font size=2 face="sans-serif"> I see Betsy, Thanks. Sort of expected Your MFM's were following that line of reasoning. </font> <br> <br><font size=2 face="sans-serif"> Pre-E is our Residents' abbreviation for preeclampsia. (Think of all the syllables saved at the end of a single day!) Did She have any bp elevation? Any chance the placenta might have been sent? Guess I already know the answer... Was enlightening to see, in the Mercer series, that Pre-E was 3-4X more prevalent than chorio, in SPT. Demonstrates that inflammation is not always infectious. </font> <br> <br><font size=2 face="sans-serif"> Guess You get enough local exposure to the anti-thromboembolic mechanisms involved (Paidas, Semin Perinatol 2005, 29:150-63). But also think it's interesting that attn is turning to immune modulating effects of Heparin (Salmon, Nat Med 11/2004, 10:1222-26). /tj</font> <br> <br><font size=2 face="sans-serif"> FRI: Sad news about Pluto. Heard Xena started the whole mess - thought they thru Her off the air? Just shows Ya' - if you're a little smaller, and keep to the periphery, those on the inside will kick You out! Just wait'll Neptune starts wandering toward the Kuiper belt, then next on the block is Uranus. >:)<br> <br> </font><font size=1 color=blue face="Arial"><b>NOTICE TO RECIPIENT:</b></font><font size=1 face="Arial"> If you are not the intended recipient of this e-mail, you are prohibited from sharing, copying, or otherwise using or disclosing its contents. If you have received this e-mail in error, please notify the sender immediately by reply e-mail and permanently delete this e-mail and any attachments without reading, forwarding or saving them. Thank you.<br> </font> <br> <table width0%> <tr valign=top> <td> <td><font size=1 face="sans-serif"><b>Betsy Hyde <elishyde@mindspring.com></b></font> <br><font size=1 face="sans-serif">Sent by: ob-gyn-l@obgyn.net</font> <p><font size=1 face="sans-serif">08/25/2006 15:01</font> <br><font size=1 face="sans-serif">Please respond to ob-gyn-l</font> <br> <td><font size=1 face="Arial"> </font> <br><font size=1 face="sans-serif"> To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net></font> <br><font size=1 face="sans-serif"> cc: </font> <br><font size=1 face="sans-serif"> Subject: Re: prolonged PP fever</font></table> <br> <br><font size=3 face="Times New Roman">On Aug 25, 2006, at 5:39 PM, </font><a href=mailto:Terrence.Jones@kp.org><font size=3 color=blue face="Times New Roman"><u>Terrence.Jones@kp.org</u></font></a><font size=3 face="Times New Roman"> wrote:</font> <br> <br><font size=2 face="sans-serif"><br> These regional differences are always interesting. After the description per Mercer & Sibai (JMFM 1996, 5:355-8), and the comparitive trial per Cunningham (AJOG 1999, 181:143-8), Our MFM's actually discourage heparin, in absence of thrombus on imaging.</font><font size=3 face="Times New Roman"> </font> <br> <br><font size=3 face="Times New Roman">The heparin was discouraged/delayed because we were told there was no good evidence that it helps if the dx is spt, and that time to defervesence does not vary based on use/nonuse of heparin if there was spt. This, apparently, was from the Cunningham Study. </font> <br> <br><font size=3 face="Times New Roman"><br> </font><font size=2 face="sans-serif"><br> Drs. Magann & Martin (Hypertens Pregnancy 2004, 23:121-7) demonstrated, as You have in this case, that the premorbid state does not always include variables associated with infection. Chorio was present in only 13% of SPT; in their 9 year series of 55 postpartum Pts. Instead, the condition may be more of an aberrant endothelial response (Pre-E present in 45%). Did Your Patient have any stigmata (of Pre-E)? </font> <br> <br><font size=3 face="Times New Roman">I don't know what the stimata of Pre-E (or even what Pre-E is....ok, I'll 'fess up) are, and either don't know/can't remember her labor course. Sorry.</font> <br> <br><font size=3 face="Times New Roman">\Betsy Hyde CNM</font> <br><font size=3 face="Times New Roman">Branford, CT</font> <br>
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