Re: UA results

From: ainsron (ainsron@sbcglobal.net)
Thu Jun 8 10:26:14 2006


Since you are outside of the first trimester, Cipro would be my drug of choice, based on the sensitivities. The overall risk is low with no pattern of anomalies in studies, although drug induced fetal cartilage damage and arthropathies are a concern in animal studies. TCN would not be a good choice, Ceftriaxone would require parenteral administration, as would Gentamycin, so I would use either if she had to be hospitalized. Levaquin is also a quinolone, like Cipro, but according to Briggs, there are no studies on its use and studies on ofloxacin, its optical isomer, has not excluded a causal relationship with birth defects.

Ronald E. Ainsworth, MD, FACOG

-----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Elrod, Darryl G Maj 48 MDOS/SGOBO Sent: Thursday, June 08, 2006 1:55 AM To: Multiple recipients of list OB-GYN-L Subject: UA results

This urine culture showed up on a 24 wk G3P1102 with a history of pyelonephritis and who was already on prophylactic macrodantin. At the time this was taken, she was seen in L&D for contractions. Her cervical length was 3.8 cm with a closed internal os.

Based on the multiple drug resistances, what would you place her on for treatment?

Organism: (1) ESCHERICHIA COLI. . . . . . . . .quantity: >100,000 CFU/ML

(1)

Mcg/ml Interp

CEFAZOLIN >2 R

+ CEFTRIAXONE <=8 S

CEFUROXIME-SODIU >2 R

CIPROFLOXACIN <=0.5 S

GENTAMICIN 1 S

TETRACYCLINE <=1 S

TRIMETH/SULFA >20 R

NITROFURANTOIN 64 I

AMOXICILLIN/CA 16 I

AMPICILLIN-GRAM >2 R

LEVOFLOXACIN <=1 S

Thanks,

Glen

//SIGNED//

D. Glen Elrod, Maj., USAF, MC

Obstetrician/Gynecologist

Chief of Obstetrics

48 MDOS/SGOBO

RAF Lakenheath, England

Telephone DSN: 314-226-8130

Comm: +44 (0) 1638 52 8130

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