Re: Bisphosphonates and osteonecrosis - from an OMFS

From: Joanne Bulley, MD (islesannie@yahoo.com)
Mon Jun 5 17:57:41 2006


I never quit. I just don't promote it. I present it as one of the options (and the only one that REALLY works for vasomotor symptoms and vaginal sexual function).

So I present the pros and cons. It does confirm my interest in Evista along with Calcium and Vitamin D and Exercise until reachin that T score of -2.5.

The major risk with HT is to the woman whose body has not had estrogen for 10-20 years and it is started de novo. (And this use was for the WHI study only as none of us in the trenches would have started a 60-79 yo woman without vasomotor symptoms on it.)

So for the symptoms for the early menopausal / perimenopausal nothing else works as well.

When the bisphosphonates were first being promoted (by the drug reps - by endocrinologists and rheumatologists) I would ask the question, "if this drug has been studied for roughly 5 years, are you serious about me potentially prescribing it for 20, 30, 40 years? What evidence do you have for me regarding long term use?" I never got any good answers.

Anybody using Forteo?

Joanne

At Mon, 5 Jun 2006, art fougner, md wrote: >
>It's enough to want to return to writing ERT Rx's again.
>
>art
>
>At Mon, 5 Jun 2006, Meenan, Anna wrote:
>>
>>I still agree with you, Kim. I'm really afraid we will be finding a
>>lot more cases now that this is known, and I prefer to wait til I see
>>how this all shakes out before aggressively promoting
>>bisphosphonates. And again, my gut feeling for myself is that I
>>would rather have a hip fracture than osteonecrosis of the jaw.
>>Really.
>>
>>Anna Meenan, MD
>>

--
Joanne Bulley, MD
Keene, NH, USA

"Love is indescribable and unconditional. I could tell you a thousand things that it is not, but not one that it is." — Duke Ellington, American jazz artist (1899-1974).





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