T3 level in pregnancy

From: Henry Gregor (henrygregor@yahoo.com)
Sun May 21 18:35:49 2006


The views of listers would be appreciated. A 35yo G1P1A2 (VIP 1, sab 1) presented at 8+wks EGA by dates, exam and sono. 1st preg'y was VIP. 2nd delivered at term, approx 5 yrs ago with PIH as well as antenatal Bell's Palsy. 3rd preg'y was SAB at 6wks, in '05.

Patient's only meds in last three months were Imitrex and antibiotic of unknown type for bronchitis. She quick smoking upon recognition of pregnancy. She had complaints of fatigue which seemed beyond that usually attibutable to pregnancy or family/occupational activities, so a TSH was drawn with her prenatal lab panel.

TSH was dec'd to .021. FT4 was nl at 1.64 ( .89 - 1.80 ). FT3 was increased at 4.9 ( 2.3- 4.2 ). She is without clinical or ROS findings suggestive of hyperthyroid- ism and has a negative PH of thyroid ds.

At first I thought perhaps HCG was contributing ... even tho' I understand it to be rather weak as a thryotropin, the levels are possibly high enough...however the T4 was normal. Is this a T3 toxicosis that should be considered pathologic and treated? Should a range of thyroid antibody studies be checked....??

Opinions appreciated.

Hank





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