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Re: Antibiotics and timing of surgery From: Efrain Ramirez (eramirezt@coqui.net) Mon Mar 20 06:50:40 2006 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Gerald P. Rodríguez: "Re: 2 cases" Previous message: Elrod, Darryl G MAJ 48 MDOS/SGOBO: "Re: Antibiotics and timing of surgery" In reply to: Elrod, Darryl G MAJ 48 MDOS/SGOBO: "Re: Antibiotics and timing of surgery" Next in thread: Dr Eberhard Lisse: "Re: Antibiotics and timing of surgery" Reply: Dr Eberhard Lisse: "Re: Antibiotics and timing of surgery" Timing of prophylactic antibiotic administration in the uninfected laboring gravida: a randomized clinical trial. Thigpen BD, Hood WA, Chauhan S, Bufkin L, Bofill J, Magann E, Morrison JC Am J Obstet Gynecol (2005 Jun) 192(6):1864-8; discussion 1868-71 ISSN: 0002-9378 Abstract OBJECTIVE: The purpose of this prospective study was to determine whether the timing of prophylactic antibiotics at cesarean delivery influences maternal/neonatal infectious morbidity. STUDY DESIGN: In this double-blind placebo-controlled trial, cefazolin was given at skin incision (group A) or at cord clamping (group B). Patients were eligible for the trial if they had labored and required a cesarean delivery. RESULTS: Over Top of Abstract a 30-month period 303 patients with singleton pregnancies entered the trial; 153-group A, 149-group B. Demographics, indication for cesarean delivery (P = .54), and operative time (P = .999), as well as rates of endometritis (RR 0.67, 95% CI 0.42-1.07), wound infection (RR 0.84, 95% CI 0.45-1.55), neonatal sepis (RR 1.28, 95% CI 0.91-1.79), and NICU admissions (RR 1.28, 95% CI 0.91-1.79) were similar between the 2 groups. CONCLUSION: There was no difference in maternal infectious morbidity whether antibiotics were given before skin incision or at cord clamping. At Mon, 20 Mar 2006, Elrod, Darryl G MAJ 48 MDOS/SGOBO wrote: > >We are still giving ancef at cord clamp. > >Glen > >//SIGNED// > >D. Glen Elrod, Maj., USAF, MC > >Obstetrician/Gynecologist > >Chief of Obstetrics > >48 MDOS/SGOBO > >RAF Lakenheath, England > >Telephone DSN: 314-226-8130 > > Comm: +44 (0) 1638 52 8130 > >Notice of Confidentiality >Under the Privacy Act of 1974, you must safeguard all information >reflected on this e-mail and, if applicable, all attachments. >Disclosure of information is IAW AFI 33-119, AFI 33-127, AFI 37-131, AFI >37-132, AFI 33-219, and PL 93-579" >This e-mail message including any attachments is for the sole use of the >intended recipient(s) and may contain confidential and privileged >information. Any unauthorized review, use, disclosure or distribution is >prohibited. If you are not the intended recipient, please contact the >sender by reply e-mail and destroy all copies of the original message. >Any questions pertaining to disclosure should be directed to the privacy >officer. > >-----Original Message----- >From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of S >Osterling M.D. >Sent: Friday, March 17, 2006 6:44 PM >To: Multiple recipients of list OB-GYN-L >Subject: Antibiotics and timing of surgery > >Many of your gyn ORs are being evaluated for timeliness of antibiotics. >The standard is within one hour of the incision. > >The big exception to this is the c-section. Most of us give 1 gram >kefzol at cord clamp. This is done at the request of pediatrics. > >Is anyone on the list giving the antibiotics prior to incision for >"better" prophylaxis? > >S. Osterling M.D. >California -- “ The greatest obstacle to knowledge is not ignorance, it is the illusion of knowledge.” Daniel J. Boorstin - Historian Next message: Gerald P. Rodríguez: "Re: 2 cases" Previous message: Elrod, Darryl G MAJ 48 MDOS/SGOBO: "Re: Antibiotics and timing of surgery" In reply to: Elrod, Darryl G MAJ 48 MDOS/SGOBO: "Re: Antibiotics and timing of surgery" Next in thread: Dr Eberhard Lisse: "Re: Antibiotics and timing of surgery" Reply: Dr Eberhard Lisse: "Re: Antibiotics and timing of surgery"

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