Re: Maternal deaths, and risk of misoprostol for missed AB

From: Betsy Hyde (elishyde@mindspring.com)
Sat Mar 18 15:31:25 2006


The RU-486 was given orally. Part 2, the misoprostil, was given off label intravaginally. This is a difference between Planned Parenthood and FDA. The women had septic abs d/t clostridia.

--
Betsy Hyde CNM
Branford, CT

On Mar 18, 2006, at 1:16 PM, Gerald P. Rodríguez wrote:

> Today's Wall Street Journal reports that Planned Parenthood in > Washington DC said yesterday that it was changing its prescribing > practices for the use of MIFEPRISTONE (Mifprex) (RU-486) in light > of two recent maternal deaths associated with its use vaginally > instead of orally. Its vaginal use is off-label and this practice > is now being implicated in the death of 6 total patients from sepsis. > > Gerald P. Rodríguez, M.D., FACOG > Santa Fe > > ~~~~~~~~~~~~~ > Quien calla otorga. > ~~~~~~~~~~~~~~ > ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

>> ----- Original Message ----- From: <igold@COX.NET> > To: "Multiple recipients of list OB-GYN-L" <ob-gyn-l@dns.obgyn.net> > Sent: Saturday, March 18, 2006 9:58 AM > Subject: Maternal deaths, and risk of misoprostol for missed AB > >> In light of the recent news linking maternal deaths to use of >> vaginal administation of misoprostol, what do you think of >> continuing its use for missed AB? Do you think oral administation >> would reduce the risk? Why? From what I understand, 6 maternal >> deaths have now been attributed to vaginal use of misoprostol (my >> sources are NPR driving home from work last night, and this >> morning's Arizona Republic newspaper) Thanks, Ingrid Gold, CNM, >> Phoenix >





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