Re: Maternal deaths, and risk of misoprostol for missed AB
From: fran wilson (530rose@msn.com)
Sat Mar 18 14:47:17 2006
Below is the press release from Planned Parenthood. It still appears to me that the drug suspected to have caused the problems is the vaginal misoprostol. Of course, there are many who would like to relate it to the "abortion pill." I am wondering about the location of the most recent two deaths. The first four were all in California, there is no mention about which clinic or which location, and the next two occurred close together but there has been no mention of location. I wonder if it is less related to the method than to some other variable that is related to that specific bacteria, such as fecal colonization. I wonder if there have been any cases of PP sepsis that can be tied to vaginal administration of Cytotec?
Fran Wilson, CNM
Kennewick, WA
"Our health centers will no longer recommend the option of administering misoprostol vaginally (misoprostol is the second drug in the two-drug medication abortion regimen). Patients will now receive misoprostol orally or buccally (where the pill is placed between the cheek and gum and dissolves). This change in protocol is effective immediately." "Our health centers will no longer recommend the option of administering misoprostol vaginally (misoprostol is the second drug in the two-drug medication abortion regimen). Patients will now receive misoprostol orally or buccally (where the pill is placed between the cheek and gum and dissolves). This change in protocol is effective immediately."
From: <igold@cox.net>
Reply-To: ob-gyn-l@obgyn.net
To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net>
Subject: Re: Re: Maternal deaths, and risk of misoprostol for missed AB
Date: Sat, 18 Mar 2006 12:22:26 -0600
Actually, if you read the link Fran sent, it infers that misoprostol is the problem. I actually heard on the NPR report that this was the case also. Ingrid
>
> From: "Gerald P. Rodríguez" <geraldpr@cybermesa.com>
> Date: 2006/03/18 Sat PM 01:17:24 EST
> To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net>
> Subject: Re: Maternal deaths, and risk of misoprostol for missed AB
>
> Today's Wall Street Journal reports that Planned Parenthood in Washington DC
> said yesterday that it was changing its prescribing practices for the use
>of
> MIFEPRISTONE (Mifprex) (RU-486) in light of two recent maternal deaths
> associated with its use vaginally instead of orally. Its vaginal use is
> off-label and this practice is now being implicated in the death of 6 total
> patients from sepsis.
>
> Gerald P. Rodríguez, M.D., FACOG
> Santa Fe
>
> ~~~~~~~~~~~~~
> Quien calla otorga.
> ~~~~~~~~~~~~~~
> ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
> ----- Original Message -----
> From: <igold@COX.NET>
> To: "Multiple recipients of list OB-GYN-L" <ob-gyn-l@dns.obgyn.net>
> Sent: Saturday, March 18, 2006 9:58 AM
> Subject: Maternal deaths, and risk of misoprostol for missed AB
>
>
> > In light of the recent news linking maternal deaths to use of vaginal
> > administation of misoprostol, what do you
think of continuing its use for
> > missed AB? Do you think oral administation would reduce the risk? Why?
> > From what I understand, 6 maternal deaths have now been attributed to
> > vaginal use of misoprostol (my sources are NPR driving home from work last
> > night, and this morning's Arizona Republic newspaper) Thanks, Ingrid Gold,
> > CNM, Phoenix
> >
>
>
>
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