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C sordellii and maternal death From: Joanne Bulley, MD (islesannie@yahoo.com) Sat Mar 18 12:45:26 2006 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Joanne Bulley, MD: "Re: C sordellii and maternal death" Previous message: Richard Chudacoff, MD: "Re: Maternal deaths, and risk of misoprostol for missed AB" Next in thread: Joanne Bulley, MD: "Re: C sordellii and maternal death" Reply: Joanne Bulley, MD: "Re: C sordellii and maternal death" 1997 report: J Clin Pathol. 1997 March; 50(3): 259–260. A fatal postpartum Clostridium sordellii associated toxic shock syndrome. A Bitti, P Mastrantonio, P Spigaglia, G Urru, A I Spano, G Moretti, and G B Cherchi Clinical Pathology Laboratory, A. Segni Hospital, Ozieri, Sassari, Italy. Abstract: Clostridium sordellii is an infrequent human pathogen. It has been demonstrated to be occasionally responsible for myonecrosis or gas gangrene. Interestingly, in the obstetric literature, some cases of postpartum maternal deaths have been associated with C sordellii infection causing a rapidly lethal toxin mediated syndrome. This is the first reported case of postpartum death in a 29 year old woman, in which a toxigenic C sordellii was isolated from the patient's blood antemortem during the fatal toxic shock, strongly indicating its role in this rare syndrome. Do we have any knowledge of the frequency of colonization in healthy women -- and the frequency of PP deaths due to Toxic Shock by C sordellii toxiins? Without those numbers we don't know whether the post RU 486 / Misoprostol incidence excedes that of birth related sepsis. -- Joanne Bulley, MD Keene, NH, USA "Love is indescribable and unconditional. I could tell you a thousand things that it is not, but not one that it is." — Duke Ellington, American jazz artist (1899-1974). Next message: Joanne Bulley, MD: "Re: C sordellii and maternal death" Previous message: Richard Chudacoff, MD: "Re: Maternal deaths, and risk of misoprostol for missed AB" Next in thread: Joanne Bulley, MD: "Re: C sordellii and maternal death" Reply: Joanne Bulley, MD: "Re: C sordellii and maternal death"

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