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Re: Preeclampsia SolvedFrom: ainsron (ainsron@sbcglobal.net)Tue Jan 31 09:50:46 2006
Actually, I answered my own question, here's the abstract: Preeclampsia: the Death of Goliath Bruce B. Feinberg In this review, a novel and unifying pathophysiologic mechanism of preeclampsia is presented whereby a minimal excess of placental immune complex production versus removal causes a proinflammatory autoamplification cascade of trophoblast apoptosis/necrosis and oxidative stress, culminating in clinical preeclampsia. This concept immediately leads to a plethora of new and robust therapeutic strategies. You can purchase the article on-line for $39. I think I'll find it elsewhere. Ronald E. Ainsworth, MD, FACOG -----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of ainsron Sent: Tuesday, January 31, 2006 6:39 AM To: Multiple recipients of list OB-GYN-L Subject: Re: Preeclampsia Solved You mean someone is finally going to get their name on the plaque for solving the problem? Isn't it at a hospital in Chicago? More importantly, is the article available to anyone in this list? Ronald E. Ainsworth, MD, FACOG -----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Harrison Sheld Sent: Monday, January 30, 2006 9:32 PM To: Multiple recipients of list OB-GYN-L Subject: Preeclampsia Solved There is a review in the American Journal of Reproductive Immunology (2006) 55:84-98 by Bruce B. Feinberg, in which the molecular pathophysiology of preeclampsia/eclampsia has been worked out, and potential prevention and treatment proposed. I know we have been down this road before, but if you have been following the recent developments in immunology it makes sense.
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