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Re: Amnisure for ruptured membranesFrom: ainsron (ainsron@sbcglobal.net)Thu Dec 1 16:06:35 2005
The point is, what did they use for a comparison in the study? I'm sure they didn't do amniocentesis and indigo carmine as a the "gold standard." Personally, I think Ferning is pretty sensitive, but it "in the eye of the beholder." I've had several times when the nurses didn't see ferning on a slide and I looked at it and found a small area, the same with lab technicians. After 30 years of looking at slides, I'm pretty aware of the subtle nuances. Unfortunately, nurses are no longer able to use the microscope to check ferning and I don't trust nitrazine as much. If this technique is good, it may be worth using it to save me a trip to the hospital to confirm the diagnosis myself. Ronald E. Ainsworth, MD, FACOG -----Original Message----- From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of RModugno@aol.com Sent: Thursday, December 01, 2005 1:21 PM To: Multiple recipients of list OB-GYN-L Subject: Re: Amnisure for ruptured membranes In a message dated 12/1/2005 3:53:20 PM Eastern Standard Time, ainsron@sbcglobal.net writes: why would I want to change what I am already doing if it is effective and cheaper? Ronald E. Ainsworth, MD, FACOG The minimum detection threshold of AmniSureR immunoassay is 5 ng/mL, which should be sufficiently sensitive to detect pPROM with an accuracy of approximately 99%. Can nitrazine or ferning claim that? Robert Modugno MD MBA FACOG Marietta, GA
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