Re: Dr. Atkinson Re: breast cancer

From: Andrew Folley (agfolley@hotmail.com)
Sun Oct 30 12:39:07 2005


In general, the rule Dr.Atkinson gave for tumor doubling times is an excellent rule of thumb particularly for breast cancers. Doubling every 3 to 6 months is the physiology which allows mammograms to be so successful in picking up breast cancers several years before they are identified clinically as a 2 cm mass. The bottom line is that you do not go from a 1 celled cancer to a 4 cm mass in 1 year. It takes several years in general. Women may have a 1 cm mass in January and then 2 cm in April, 4 cm in Sept and tennis ball sized (7cm) by then end of the year. Totally consistent with the doubling time physicians refer to.

Arimidex and tamoxifen actually do work the same way. They prevent the stimulation of estrogen receptor positive tumors. Arimidex prevents estrogen porduction from the aromitization of testosterone and tamoxifen blocks estrogen by being tying up and blocking receptor tumors on the tumor. End result is estrogen stimulation of tumor is prevented. I do not know about the costs. Tamoxifen and Arimidex have been both higly successful in preventing reoccurence. The diference between the two is maybe 2 or 3 percentage points with Arimidex having the edge. andrew

>From: GIN11153@aol.com
>Reply-To: ob-gyn-l@obgyn.net
>To: Multiple recipients of list OB-GYN-L <ob-gyn-l@dns.obgyn.net>
>Subject: Dr. Atkinson Re: breast cancer
>Date: Sat, 29 Oct 2005 02:29:01 -0500
>
>I asked my husband( general surgeon) about what you said about tumor
>doubling times and he said one can't say what you mentioned, as it
>totally depends
>on the type of tumor, aggressive or not, etc.
>
>Plus, there is a very large difference between Tamoxifen and Arimidex-they
>don't work quite the same at all and are prescribed for different types of
>tumors, whether someone is pre or post menopausal, etc.
>
>MRIs have a very high false positive rate as it's overly sensitive(I have
>had 2 a year apart now) and the cost is less than the $3000-3500 cost for
>genetic screening that insurance rarely pays for!
>
>Gail Neuman RNC CPHW SNP LNC-one year breast cancer survivor!!
>listowner of LegalNurseConsulting@yahoogroups.com
>certified high risk OB/legal nurse consultant
>Notary Public/Certified Loan Signing Agent
>Tustin, CA
>





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