Re: Tamoxifem & Mirena

From: Peter Wein (pwein@unimelb.edu.au)
Sat Oct 29 07:05:38 2005


We have found the same - the thickening seen on ultrasound seems to really be a subendometrial cystic change, with the overlying endometrium being bland.

--
Peter Wein

Atkinson, Samuel M wrote:

>Endometrial cancer is reported with long term Tamox but I have done many >biopsies for the increaded endometriums on Tamox and they are invariably >neg. At D&C there is no endometrium at all. I think, but obv cannot >prove that Tamox causes an US pix of thickened endomet that is really a >fibrosed thickened myometrium that gives a false positive report. Thus >I now stop with a negative Pipelle. Certainly agree with the Mirena >unless you know she is PM for sure (like an FSH). Pf course 1.12 is not >excessive for a menstruating woman!. > >-----Original Message----- >From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Joanne >Bulley, MD >Sent: Thursday, October 27, 2005 5:19 PM >To: Multiple recipients of list OB-GYN-L >Subject: Tamoxifem & Mirena > >50yo G2P2 Breast CA 2000 (because I insisted she have her mammograms in >'99 & '00 - she tried to argue her way out). > >Treated with excision / sentinel nodes and radiation therapy. Followed >by 5 years Tamoxifen which was completed 9/00. > >Mirena placed for contraception 08/04. > >Erratic bleeding during the summer. > >US done (because of Tamoxifen even though most likely benign >peri-menopausal bleed with Progesterone IUD) > >US IUD in place. Some fibroid change. Endometrium 1.12 cm. Ovaries >Fine. > >Thoughts, anyone? > >-- >Joanne Bulley, MD >Keene, NH, USA > >"Love is indescribable and unconditional. >I could tell you a thousand things that it is not, but not one that it >is." >- Duke Ellington, American jazz artist (1899-1974). >





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