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GEN: NEJM Articles Weigh In on Routine HIV Screening From: art fougner, md (evsono@pipeline.com) Thu Feb 10 06:55:51 2005 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Elrod Darryl G MAJ 48 MDOS/SGOBO: "Osteoporosis" Previous message: Terrence.Jones@kp.org: "Re: TENS unit and labor" Today's NEJM has some coverage of expanded HIV Testing ... here's an excerpt from the editorial ... Routine Screening for HIV Infection — Timely and Cost-Effective Samuel A. Bozzette, M.D., Ph.D. In the United States, HIV infection is generally discovered at an advanced stage, usually in the course of medical care and often during care for complications of AIDS. Earlier diagnosis would be far preferable, because it could speed access to appropriate care and increase the proportion of HIV-infected patients receiving care, thereby improving the quality of care for persons and populations.1 Two articles in this issue of the Journal indicate that widespread use of routine screening could offer these benefits and more at a reasonable cost. Paltiel and colleagues2 and Sanders and colleagues3 both predict that widespread use of routine screening will yield substantial benefits for HIV-infected patients. Paltiel et al. estimate that the average CD4 count at the detection of HIV infection would rise from 154 to 210 cells per cubic millimeter and that the proportion of cases diagnosed at the time of an opportunistic complication would drop. These factors are important, because earlier access to antiretroviral therapy is likely to make it easier to suppress viral replication, improve immunity, and reduce drug-related adverse effects.4 Consistent with this outcome, both studies estimate that the effects of screening would extend survival by 1.5 years for the average HIV-infected patient. More ...http://content.nejm.org/cgi/content/full/352/6/620 art -- art fougner, md "If you don't know where you are going, you will wind up somewhere else." Lawrence Peter Berra Next message: Elrod Darryl G MAJ 48 MDOS/SGOBO: "Osteoporosis" Previous message: Terrence.Jones@kp.org: "Re: TENS unit and labor"

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