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Re: Estrogen and breast cancer From: DoctorJoe@aol.com Sat Jul 24 11:34:31 2004 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: RModugno@aol.com: "Chlamydia in Pregnancy" Previous message: Kaycnm@aol.com: "Re: Inverted uterus" Maybe in reply to: Richard Chudacoff, MD: "Estrogen and breast cancer" Next in thread: Richard Chudacoff, MD: "Re: Estrogen and breast cancer" Reply: Richard Chudacoff, MD: "Re: Estrogen and breast cancer" In a message dated 7/23/04 09:39:39, rchudacoff@mylinuxisp.com writes: > I am trying to break down the estrogen/breast cancer/WHI dilemma to its > basic components, and have whittled it down to this question: assuming that a > patient is GOING to get breast cancer (since if they don’t, the whole issue of > HRT is moot) is it better to be on estrogen or not on estrogen? I remember > the JAMA article around 1998 (Trudy Bush I believe) which stated that women > taking estrogen had a more well differentiated, therefore more treatable form of > cancer than women who developed breast cancer not on estrogen. What are your > feelings on this? If so, and breast women do better if they develop breast > CA on HRT, would it not make sense to start, even if there are no menopausal > symptoms? > I'm wondering about the logic of discounting women if they're not "GOING to get breast cancer." I don't think the issue of estrogen is moot in any woman prospectively. The reason (I thought) that women who got breast Ca ON estrogen had better differentiated tumors is that it was possible the estrogen itself overly stimulated normal tissue to initiate carcinogenesis, while the women OFF estroge had "naturally occurring" cancer, which tended to be, well, more malignant (i.e. undifferentiated). So I don't know how the logic would go with YOUR line of thought here. Joe P. Next message: RModugno@aol.com: "Chlamydia in Pregnancy" Previous message: Kaycnm@aol.com: "Re: Inverted uterus" Maybe in reply to: Richard Chudacoff, MD: "Estrogen and breast cancer" Next in thread: Richard Chudacoff, MD: "Re: Estrogen and breast cancer" Reply: Richard Chudacoff, MD: "Re: Estrogen and breast cancer"

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