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Re: Question: fosamax and calcitonin at the same time From: Charlie Chambers (cchamber@gorge.net) Fri Jan 23 10:28:59 2004 Messages sorted by: [ date ][ thread ][ subject ][ author ] Next message: Braun, R. Daniel: "Capt. Kangaroo died" Previous message: Robert Modugno MD: "Fat chance, says US, to anti-obesity plan (http://theaustralian.com.au report)" In reply to: Joanne Bulley, MD: "Re: Question: fosamax and calcitonin at the same time" I would be very hesitant to combine therapies. i would be more inclined to use monotherapy and if those clearly fail then parathyroid hormone. The data are sparse and nonexistent with regards to fracture data and combination therapies. Increasing BMD does not correlate in a linear fashion to fracture risk. Seems too often that people want to combine therapies with the assumption that if one works, two might be better. A false assumption at best. ************************************************************************ ****** Charlie Chambers -- Hood River, OR USA cchamber@alumni.rice.edu "All good things...come by grace, and grace comes by art, and art does not come easy." Norman Maclean ************************************************************************ ******* On Jan 21, 2004, at 3:51 PM, Joanne Bulley, MD wrote: > I just took the reference back to the office - at a recent (well - > October) update one day course - there was a presentation on this exact > study. > > NO! You do not give them together (fosamax and calcitonin analogues) > because the fosamax binds to the osteoclasts (stopping their function > of > reabsorption) and the calcitonin requires active osteoclasts to > rebuild. > > I just had the syllabus at home for a discussion off list that Terrence > Jones and I were having about the WHI etc - but I took it back to the > office today! > > I can *try* to remember to look it up tomorrow. > > Joanne Bulley, MD > > At Wed, 21 Jan 2004, Mary Nachreiner wrote: >> >> Question: Is it necessary or efficacious to give fosamax and >> calcitonin at >> the same time. Patient also receiving evista in conjunction, for >> treatment >> of bone pain and refracture of t-11 due to osteoporosis. > > -- > Joanne Bulley, MD > Keene, NH, USA > > ----- > "It is easier to understand a nation by listening to > its music than by learning its language" -Anonymous > Next message: Braun, R. Daniel: "Capt. Kangaroo died" Previous message: Robert Modugno MD: "Fat chance, says US, to anti-obesity plan (http://theaustralian.com.au report)" In reply to: Joanne Bulley, MD: "Re: Question: fosamax and calcitonin at the same time"

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