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Re: maternal hep BFrom: Efrain Ramirez (eramirezt@coqui.net)Tue Sep 30 15:34:17 2003
This is what ACOG says: I think it's rather clear.. "Perinatal Management. The combination of passive and active immunization, as outlined here, has been particularly effective in reducing the frequency of perinatal transmission of hepatitis B virus. Several investigations conducted in Asian nations have shown that passive and active immunization of the newborn is 85-95% effective in preventing perinatal transmission of hepatitis B virus. The Centers for Disease Control and Prevention and the American College of Obstetricians and Gynecologists recommend hepatitis B virus screening for all pregnant women. Pregnant women should be routinely tested for HBsAg during an early prenatal visit. If, at the time of admission to the hospital for delivery, the test has not been performed or the results are not available, the HBsAg test should be done. Women in high-risk groups who initially test negative for hepatitis B virus should be targeted for vaccination if they have not been vaccinated previously. Seropositive women should be encouraged to inform their children and sexual partners of the need for testing and vaccination. Serum transaminases should be measured in seropositive women to detect biochemical evidence of chronic active hepatitis. If the test results are abnormal or if the liver is palpable, the patient should be evaluated further to determine whether the disease is acute or chronic. The Centers for Disease Control and Prevention recommends universal active immunization of all infants born in the United States (6). The immunization schedule for infants of women who have been screened and are negative should be started preferably before discharge, but by no later than 2 months of age. Infants of women who are known to be HBsAg positive or whose status is unknown should have both passive and active immunization treatment. It should be given simultaneously at different sites intramuscularly and started within 12 hours after birth. Such a strategy will prevent postnatal and neonatal acquisition of hepatitis B virus in most cases. The physician responsible for the care of a newborn delivered to a mother with chronic hepatitis B should be informed of the mother's carrier status so that the appropriate doses of hepatitis B virus vaccine and HBIG can be given as soon as possible following delivery."
At Mon, 29 Sep 2003, Richard Chudacoff, MD wrote:
>
-- "The opposite of a correct statement is a false statement. But the opposite of a profound truth may well be another profound truth."
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