F/U 15 Week Echo Twin A ,NT4.3 ;Twin B NT 1.6, nl chromo

From: Patricia Sabb (pcsabb@wisc.edu)
Thu May 29 11:03:17 2003


35 yo physician with lower(closer to cervix) Twin A 46XX, NT 4.3; Twin B 46XY, NT 1.6. Echo at 14 wk 6 day showed no obvious cardiac abnormalities.

Risk of abnormality not detectable on US prenatally? Is it really 10%?

If selective reduction of lower twin with increased nuchal, risk to other twin?

Maternal factors influence NT? Since twins with discordant NT, more likely to signify abnormality?

How can you explain increased NT at 11-14 wk with a subsequent normal outcome? Why was it elevated originally?

Patient is naturally pessimistic (side effect of being a doctor and seeing the worst) and is having a hard time deciding next course of action.

Thank you for your help.

--
Patricia Sabb, MD




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