Re: WHI : Hormones and Stroke Risk
From: art fougner, md (evsono@pipeline.com)
Thu May 29 08:08:03 2003
answering machine message:
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for questions regarding the WHI - hold on for at least 2 weeks until the
doctors have had a chance to review the article.
art
At Wed, 28 May 2003, Myer Bornstein wrote:
>
>“Estrogen plus progestin therapy increased the risk for probable dementia in
>postmenopausal women aged 65 years or older. In addition, estrogen plus
>progestin therapy did not prevent mild cognitive impairment in these women.”
>
>Note that the study only showed PROBABLE dementia and did not prevent mild
>cognitive impairment. Hasn’t been shown there is a slight decrease in
>cognitive impairment as people age. I also agree with Dan that study has
>flaws. What happens when a menopausal women starts on HRT in the early
>fifties? I do not think all the answers are in at present, BUT the media is
>harping on it aging. . the call are restarting to come in to the office
>what should I do. As it has been stated by others on the list we will need
>to CYA.
>
>Myer
>
>--
>Myer S. Bornstein, MD, MMM, FACOG, FACPE, CPE
>
>-----Original Message-----
>From: ob-gyn-l@obgyn.net [mailto:ob-gyn-l@obgyn.net] On Behalf Of Braun, R.
>Daniel
>Sent: Wednesday, May 28, 2003 9:32 AM
>To: Multiple recipients of list OB-GYN-L
>Subject: Re: WHI : Homones and Stroke Risk
>
>Excuse ME!!!!!!!!!!!!!!!!
>
>We have to remember that all of this information is coming from a single
>study that is being reported 15 different ways. How many academic careers is
>this making??
>
>This may well be a Large randomized, controlled, double blinded study. But
>it is still just ONE study. We all agreed that it had many flaws in it when
>it was first reported. It still has all those same flaws.
>
>e.g. in the dementia portion, the average length of time in the study was 4
>years. Prior studies showed it took either 7 years or a higher dose of
>estrogen to make any beneficial difference in outcomes.
>
> Remember the still unvalidated “Zeta” statistic!!!!!!!!!!
>
>Just because the media are hyping the hell out of this ONE study, doesn’t
>mean that we have to buy into it. WE can ask for more studies with a
>different population, etc.
>
>Remember if you tell a lie often enough, no matter how egregious it is,
>people will start to believe it.
>
>Dan
>
>-----Original Message-----
>From: DoctorJoe@aol.com [mailto:DoctorJoe@aol.com]
>Sent: Wednesday, May 28, 2003 7:56 AM
>To: Multiple recipients of list OB-GYN-L
>Subject: Re: WHI : Homones and Stroke Risk
>
>In a message dated 5/28/03 07:06:54, dkrell@msn.com writes:
>
>Conclusions Estrogen plus progestin increases the risk of ischemic stroke
>in generally healthy postmenopausal women. Excess risk for all strokes
>attributed to estrogen plus progestin appeared to be present in all
>subgroups of women examined.
>
>So I guess God INTENDED women to have menopause - maybe because of the apple
>and the serpent and all that stuff about leading poor Adam astray - and if
>we try to AVOID it, something bad might happen. Geeze!
>
>Joe P.
>
--
art fougner, md
ich bin ein New Yorker
